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Metabolic issues and melanomas, related?

 
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gaitinalong
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Joined: 29 Jun 2011
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Location: Tennessee

PostPosted: Sun Oct 16, 2011 12:26 pm    Post subject: Metabolic issues and melanomas, related? Reply with quote

ErinR76 wrote:
it's my thread, I can hijack it if I want to:

you said, " I have a metabolic horse who is starting to deal with melanoma nodules in his ears and around one eye."

Do you think the two are related?

My gray mare has a melanoma nodule under the skin of the right ear, about the size of a chicken egg. So far I think I'm going to have it removed soon. So keep me informed on your research; inquiring minds want to know!!!


I have always known grays and whites are prone to melanomas.

My metabolic horse is a solid liver chestnut and his melanomas are not in the typical spots.  Three in his ears, one over an eye and they didn't start to appear until the last two years with the ear nodules in the last 14 months.  They are all pea-sized at this time.

He has had an enlarged pituitary gland since the EMS exploded on him 4+ years ago.  So even though he is now 24, given all these out-of-the-norm things especially that he's a liver chestnut, yes I think his melanomas are connected to his metabolic issues but I sure could be wrong.

I did find these links and I have forwarded them to someone who is familiar with melanomas, sarcoids, etc., for some input.

I don't want to put anything on my horse or in him that might end up setting off a "melanoma firestorm".  The vet thinks they are better left alone until they start getting active but, opinions on that seem to be equally divided

I found these two articles so far; I am still trying to find something that might connect metabolic issues to melanomas in certain instances but it's slow-going.  My eyes wear out quick from earning a living in front of a computer screen the last 38 years of my work career - lol lol

Anyone feel free to jump in

http://drcollatosblog.highdeserte...0/04/4282010-equine-melanoma.html

http://www.thehorse.com/ViewArticle.aspx?ID=12755
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PasoBaby_CarolU
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PostPosted: Sun Oct 16, 2011 2:39 pm    Post subject: Reply with quote

I read The Horse article on Melanomas in the magazine.  What I got from it was that the external ones are not fatal, but the internal ones are.  And of course, you don't know about those until they are found at necropsy.  

I have studied metabolic issues for 5 years now, with two horses who are IR, one also display's Cushings signs.  I have talked to Dr.'s Kellon and Frank, two leading experts in the U.S.   What I have found from reading TONS is that they are a long ways from understanding the metabolic systems of horses.   My Cushings mare didn't respond at all to Pergolide (affects the pituitary), but was off on her T4 so tried her on Thyro-L instead, she responded incredibly.   My fully IR mare I tried everything suggested on, J-herb, Chasteberry juice, diet, and the only thing that got her Insulin down was Metformin.   The study didn't show any gain after a 10-day treatment, but it was the only thing that moved her Insulin down, so I put her back on it.   It took nearly 9 months, but her Insulin level dropped to normal values.  She is still IR, but sound and managed with diet and no medication now.  

After trying all these things and dealing with local vets, it all seems like shooting in the dark to see what works for your horse.
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gaitinalong
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PostPosted: Sun Oct 16, 2011 7:18 pm    Post subject: Reply with quote

PasoBaby_CarolU wrote:

After trying all these things and dealing with local vets, it all seems like shooting in the dark to see what works for your horse.


That should be the statement that precludes any reply to a horse owner newly dealing with metabolic issues.  It should be Pinned at the top of the Health Section of every horse forum known to mankind:)

My EMS guy was diagnosed 4-1/2 yrs ago and if I'd listened to either of the vets (from different facilities) and about 10 years apart in vet school, he might not be here.

You don't want to see a puzzled look or shrug of the shoulders follow their comments of "just watch his diet---------------" as the unfinished sentence just sort trails over the cliff.

I didn't know anything about Dr. Kellon back then.  I did know about three equine nutritionists in two states that helped me get Duke started on the right diet track right away.  If they didn't save his life, they did save him from a lot of pain because, to-date and knock-on-wood, he has never even been close to a laminitic issue.

It is amazing the difference in early "insulin spike" symptoms between my two metabolic horses.  While things are the same, they are still different between them, if that makes any sense; which nothing about these diseases does

I am so glad your horse is back on track and as healthy as she can possibly be with her current regimen.
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misstux
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PostPosted: Mon Oct 17, 2011 1:25 am    Post subject: Reply with quote

I corresponded with Dr. Kellon too about my late Dusty, who was IR/PSSM.  The metabolic guys tend to have more health issues than other horses.
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ErinR76
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PostPosted: Tue Oct 18, 2011 7:15 pm    Post subject: Reply with quote

So this one under the skin behind her ear, that is growing slowly but surely since June, my vet said we should take it out. Does anyone here think that is a bad idea? I feel pretty comfortable taking it out. I'm afraid that leaving it to get bigger will shorten her life span. But I'm no doctor. This is a vet who tends to be conservative, not in it for the money and the surgery will only cost around $200. So I trust him. What say y'all?
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PasoBaby_CarolU
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PostPosted: Tue Oct 18, 2011 7:25 pm    Post subject: Reply with quote

Baby has had melanomas under her tail for years.  The vet said we could take them off, but they'd just grow back.   And there is the risk of infection, especially in that area.  So, I left them alone.  There are more there now, but they don't seem to bother her.  She's 25 now.

Only you can decide what to do.
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Carol Nudell
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"The path to your horse's heart lies through your own."

Rumors are carried by haters, spread by fools, and accepted by idiots.  - Words of Wisdom - Mhar

‎"Great minds discuss ideas; Average minds discuss activities; Small minds discuss people." - Eleanor Roosevelt
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Mandy'sMarty
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PostPosted: Tue Oct 18, 2011 7:43 pm    Post subject: Reply with quote

Check out Buck Mountain Botanicals. Review the information regarding Neoplasene and it's effect on tissue containing cancer or virus. Read the case histories and view the images.

www.buckmountainbotanicals.net/pdf/clinical_​guide.pdf

I used it to treat a huge tumor growing on the tail of my lab, Bodacious, last year. Stunning results. I have a slide show of about 60 images that chronicle the treatment and healing. One day I'll find a share site where I can upload the slide show.
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ErinR76
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PostPosted: Tue Oct 18, 2011 8:43 pm    Post subject: Reply with quote

page  not found, although I'd like to see it...
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Mandy'sMarty
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PostPosted: Wed Oct 19, 2011 12:03 am    Post subject: Reply with quote

Try this instead: Use that link to gain entry to the Buck Mountain site and then go to the link for "Home".

Then, look under the Pet Health Flyers. The document I initially was directing you to previously is there titled as
"Relevant Neoplasene documents from Buck Mountain Botanicals: Discussion and Case Histories."

The other documents contained there are also worth reading, particularly
" Fox's AVMA Atlanta 2010 Conference Paper -
Preferential Destruction of Cancerous Tissue".

It was at that AVMA convention where I met Dr. Fox, although I had already begun the Neoplasene protocol on my Labrador a couple of weeks prior. I had acquired the Neoplasene from my vet. It is only available through veterinarians, commercial herdsmen and pet stores.
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So as to have the life
That is waiting for us.

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ErinR76
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PostPosted: Wed Oct 19, 2011 1:52 am    Post subject: Reply with quote

Wow. Check out the horse case study on page 70!!! Grooooody to the max!!!

I'll ask my vet if he's ever heard of this treatment and show him the paper. Thanks.
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tchofclas
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PostPosted: Wed Dec 14, 2011 12:02 am    Post subject: Reply with quote

I had a vet tell me all grey horses die of cancer if they live long enough. I didn't put much stock in it because he also told me my mare didn't have heaves, but changed his opinion after I chased her around a bit and he listened to her breathing again. At the time she had "tumors" on the upper inside of her rear leg, about the size of marbles. When they  became closer to the size of oranges, I took her to OAC at Guelph, Ontario, where our Vets train. The consulting  Vet told me melanomas in humans are 90% cancerous, and 10% benign, in horses, its the opposite, 90 percent benign, 10 percent cancerous. Doesn't sound to me like all grey horses die of cancer!
I had them removed because I wanted to breed the mare again, and was worried about the foal irritating them. The Vet did say there was another mass under her udder, but they'd have to remove mammary glands, and it would be a very invasive procedure. I'm not sure how many more years she lived, would have to go back and look it up, but she was 14 at the time of the operation, and had at least 3 more foals, and I don't believe the mass was the cause of her later illness, was mostly complications from a leg injury, but I eventually ended up putting her down. the operation was done about 15 years ago, so opinions may have changed since then. I have another grey mare who has had one under her tail since she was about 3, now 13, and never seems to bother her, touch wood! Both of these mares were Arabian , by the way, and not related.
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ErinR76
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PostPosted: Wed Dec 21, 2011 2:55 am    Post subject: Reply with quote

I'm trying to save up the $200 to get the operation done. The mass has grown not quite double the size it was in May. I'm hoping we take it off and that's the end of that particular lump. She has others that have not grown in size.
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gaitinalong
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PostPosted: Wed Dec 21, 2011 1:14 pm    Post subject: Reply with quote

ErinR76 wrote:
I'm trying to save up the $200 to get the operation done. The mass has grown not quite double the size it was in May. I'm hoping we take it off and that's the end of that particular lump. She has others that have not grown in size.


Here's hoping the operation will be a success and that you won't have to go thru that again.

Duke has been on an herbal blend a few weeks after we first started this thread; hard to believe that was October, where did the time go?

Anyway, the company I buy all the herbs from suggested to try these two products.  Both involve keeping the blood circulating.

http://www.herbs4horses.com/-c-38_68.html  The company's owner said this product takes a really long time to see any results and not all horses may be helped.  So far what I see is that Duke has stopped itching his ears all the time.  There aren't any new melanomas and the ones he has have not grown.

Then there's this product whose primary purpose is increasing blood flow; it is generally used for arthritic horses.  Since Duke and my other 20-something are on NSAIDS for arthritis I put both of them on this product.  From that perspective, the product has made an amazing difference to the good in the fluidity of their movement.

http://www.herbs4horses.com/-c-38_5.html

Whether or not these products will disolve the current melanomas and permanently prevent new ones remains to be seen but they do make both horses feel a lot better.

This company's Allergy Herbal Blend has been the ticket for my dust/mold/pollen allergy horse for the last several years.  Tri Hist used to amp this horse up really bad and it didn't work near as well as this herbal blend.  The herbal blend mellows him out so much that I wish I could keep him on it all year.  I don't because he doesn't need it in the winter plus I'm afraid he'll build a tolerance to it; I have to double dose him in the height of allergy season as it is

The Boys are going to look like one big herbal garden before too long
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